bildLorenz S

Structural mechanisms of HECT-type ubiquitin ligases.

Biological Chemistry (invited review), in press



Sander B, Xu W, Eilers M, Popov N, Lorenz Shuwe1

A conformational switch regulates the ubiquitin ligase HUWE1.

eLifedoi: 10.7554/eLife.21036. (2017); PMID: 28193319



Lorenz S, Bhattacharyywebsite1a M, Feiler C, Rape M, Kuriyan J

Crystal structure of a Ube2S-ubiquitin conjugate.

PLoS One 11 (2): e0147550 (2016); PMID: 26828794



Lorenz S, Deng T, Hantschel O, Superti-Furga G, Kuriyan Jkinase

Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity

Biochemical Journal, 468(2):283-91 (2015); PMID: 25779001



Lorenz S, Cantor A C, Rape M, Kuriyan Jfigure1a

Macromolecular juggling of ubiquitination enzymes.

BMC Biology 11:65 (2013); PMID: 23800009



Wickliffe KE, Lorenz S*, Wemmer DE, Kuriywickian J, Rape M

The mechanisms of linkage-specific ubiquitin chain elongation by a single-subunit E2.

Cell 144: 769-81(2011); PMID: 21376237

* co-first and co-corresponding author



oxf Lorenz S, Vakonakis I, Lowe ED, Campbell ID, Noble ME, Hoellerer MK

Structural analysis of the interactions between paxillin LD motifs and alpha-parvin

Structure 16 (10): 1521-31 (2008); PMID: 18940607



Sumper M, Lorenz S, Brunner Esumpi

Biomimetic control of size in the polyamine-directed formation of silica nanospheres.

Angewandte Chemie International Edition 42 (42): 5192-95 (2003); PMID: 14601169



Kkroegiröger N, Lorenz S, Brunner E, Sumper M

Self-assembly of highly phosphorylated silaffins and their function in biosilica morphogenesis.

Science 298 (5593): 584-86 (2002); PMID: 12386330



Spudich G, Lorenz S, Marqusee Sgiuli

Propagation of a single destabilizing mutation throughout the Escherichia coli ribonuclease HI native state.

Protein Science 11 (3): 522-28 (2002); PMID: 11847275



Other publications:

Lorenz S

Ubiquitous and influential


Lorenz S

Allgegenwaertig und einflussreich


Ries L, Lorenz S

Ubiquitin-Ligasen: Heisse Targets für die Wirkstoffentwicklung

BIOspektrum Vol 22 (3): 244-246 (2016)


Lorenz S

Das Ubiquitin-System: Ein regulatorisches Wunderwerk

GIT Laborfachzeitschrift 3/2015: 33-35 (2015)


Lorenz S

Lindau: Hitting the dancefloor with nobel laureates.

The Biochemist 30 (1): 44a (2008)


Lorenz S

Toxicology. E.U. shifts endocrine disrupter research into overdrive.

Science 300 (5622): 1069 (2003); PMID: 12750489


Lorenz S

Germany. Publishers and universities wrestle over rights.

Science 299 (5615): 1959 (2003). PMID: 12663884