Our lab is integrated into the Department of Structural Biology of the Rudolf Virchow Center, headed by Prof. Caroline Kisker and Prof. Hermann Schindelin. We have state-of-the-art instrumentation for the preparation of proteins and peptides, including numerous FPLC and HPLC systems.
A wide range of modern biophysical techniques are also available, such as
- isothermal titration calorimetry (ITC)
- analytical ultracentrifugation (AUC)
- bio-layer interferometry (BLI)
- microscale thermophoresis (MST)
- dynamic light scattering (DLS)
- multi-angle light scattering (MALS)
- differential scanning calorimetry (DSC)
- circular dichroism spectroscopy (CD)
- rapid mixing: quenched-flow and stopped-flow
- mass spectrometry (ESI, MALDI, MS/MS)
We have access to the high-field NMR facility at the nearby University of Bayreuth (directed by Prof. Paul Rösch), which is the home of Germany’s first 1 GHz magnet besides 900 MHz, 700 MHz, 600 MHz, and 400 MHz spectrometers.
Our studies also benefit from an extensive imaging platform at the Rudolf Virchow Center that allows a wide range of microscopic applications, including atomic force microscopy (AFM) and cryo EM.